Our customers are university and research institutions, hospitals, public health and commercial laboratories, biotechnology and pharmaceutical companies, as well as applied laboratories that include food safety and environmental quality. With a focus on quality and customer service for 70 years, our products advance the discovery process and improve healthcare. (NYSE: BIO and BIOb) is a global leader in developing, manufacturing, and marketing a broad range of innovative products for the life science research and clinical diagnostic markets. “Our columns deliver run-to-run uniformity to support preparative scale purifications and/or method development for new target proteins, as well as to improve existing workflows.”īio-Rad Laboratories, Inc. “Similar resins can give different results for different target molecules, and with Bio-Rad’s EconoFit Column Packs our customers can easily perform resin scouting to identify the one which yields the best outcome for their chromatography application,” said Ertan Ozyamak, PhD, Bio-Rad Global Product Manager for lab-scale chromatography products. Columns are available in 1 ml and 5 ml sizes. The convenient, easy-to-use and disposable column format is fully compatible with Bio-Rad’s NGC Chromatography Systems and other commonly used chromatography systems. The new packs include mixed-mode, cation, and anion exchange resin columns, as well as a pack designed for His-tag protein purification. BT, breakthrough.Wide Selection of Resins in New, Convenient Column Format to Support the Development of Protein Purification Workflowsīio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostic products, announce the launch of EconoFit Low-Pressure Prepacked Chromatography Column Packs to support resin screening experiments in the development of protein purification workflows.īio-Rad’s range of EconoFit Columns provides a wide selection of resins in a prepacked format, allowing customers to simply screen resins and select the optimal chemistry for different target molecules. The sample was loaded onto the column in 40 mM sodium acetate, pH 5.0 + 30 mM sodium chloride, washed, and then eluted with 40 mM sodium acetate, pH 5.0 + 1 M sodium chloride. Comparison of Nuvia S and other commercially available CEX media. Binding of polyclonal human IgG by Nuvia S media. Fully supported for regulatory submissionįig 1.Flexibility in use for capture or polish steps.Chemical stability to withstand repetitive clean-in-place cycles.Reduce capital and operating expenses through the use of smaller columns.Reduce costs and space requirements by decreasing buffer consumption.Reduce cycle-time and increase productivity by operating at higher flow-rates.Use less media to purify a given amount of product.Nuvia S delivers value and flexibility, by allowing users to: The media delivers superior binding capacity over a wide operational window, making it the tool of choice for a wide range of downstream processes. Nuvia S is a flexible alternative that may be used both as a capture or polishing solution. Nuvia S provides very high capture and exceptional flow properties designed to meet current and future process needs. Nuvia™ S is an ultra high-capacity, next-generation cation exchange media built on the industry proven UNOsphere base matrix technology. Article: The Effect Of Conductivity On Dynamic Binding Capacity On CEX Resins Technical Note: Nuvia™ S Media - A High-Capacity Cation Exchanger For Process Purification Of Monoclonal Antibodies
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